Characteristics of individuals with tuberculosis in an urban, poor population in Osaka City, Japan — a case-control study

Authors

  • Akira Shimouchi Nishinari District Public Health Office, Osaka, Japan; The Research Institute of Tuberculosis, Japan Anti-tuberculosis Association, Tokyo, Japan
  • Yuko Tsuda Osaka City Public Health Office, Osaka, Japan
  • Jun Komukai Osaka City Public Health Office, Osaka, Japan
  • Kenji Matsumoto Osaka City Public Health Office, Osaka, Japan
  • Hideki Yoshida Osaka City Public Health Office, Osaka, Japan
  • Akihiro Ohkado The Research Institute of Tuberculosis, Japan Anti-tuberculosis Association, Tokyo, Japan

DOI:

https://doi.org/10.5365/wpsar.2018.9.1.005

Abstract

Objective: To identify individual characteristics related to the development of pulmonary tuberculosis (PTB) among residents in the Airin area (Airin), Osaka City, Japan.

Methods: We conducted a retrospective case-control study of individual characteristics potentially related to the development of PTB by comparing PTB patients and residents without tuberculosis (TB) in Airin. The following binominal data of characteristics were compared: age (< 65 or > 65); body mass index (BMI) (< 18.5 or > 18.5); diabetes mellitus (diagnosed or not diagnosed); smoking (currently smoking any amount or not smoking); and alcohol use (currently drinking any amount or not drinking).

Results: We compared the individual characteristics of 192 PTB patients notified from January 2015 to December 2018 and 190 residents of supportive houses who attended a health education programme from April 2016 to March 2018.

Univariable analysis showed that the following characteristics were significantly related with PTB: BMI < 18.5 (odds ratio [OR]: 6.54, 95% confidence interval [CI]: 3.58–11.97, P < 0.001) and current alcohol use (OR: 1.88; 95% CI: 1.24–2.85, P = 0.003). Multivariable analysis showed similar results: BMI < 18.5 (adjusted odds ratio [aOR]: 6.90, 95% CI: 3.72–12.79, P < 0.001) and current alcohol use (aOR: 2.15, 95% CI: 1.36–3.42, P = 0.001).

Discussion: Undernutrition and alcohol use are individual characteristics associated with PTB among residents in Airin, Osaka City. To strengthen the TB control programme further, it is suggested to develop new programmes for primary prevention.

References

Japan Anti-Tuberculosis Association, Statistics of TB 2016, Tokyo, 2016, p4.

Tuberculosis Control in Nishinari District- Report of Special TB Project in Nishinari District, Nishinari Public Health Office, March 2017, p3, p18(Japanese).

World Health Organization, The END TB Strategy, Global strategy and targets for tuberculosis prevention, care and control after 2015. A67/11. March 2014, p18.

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Restrepo BI, Diabetes and tuberculosis, Microbiol Spectr, 2016; 4/ TNM17-0023-2016.

Slama K, ChiangC-Y, Enarson DA, et al. Tobacco and tuberculosis: a qualitative systematic review and meta-analysis, Int J Tuberc Lung Dis 2007; 11:1049-1061.

Cegielski JP, Arab L, Cornoni-Huntley J. Nutritional risk factors for tuberculosis among adults in the United States, 1971-1992. Am J Epidemiol.2012;176:409-422.

Shimouchi A, Fight against urban tuberculosis problems and program effects in Osaka City, Kekkaku 84, 727-735,2009. (Japanese, English abstract)

Bhargava A, Chatterjee M, Jain Y, et al. Nutritional Status of Adult Patients with Pulmonary Tuberculosis in Rural Central India and Its Association with Mortality, PLOS ONE, 2013; 8: e77979.

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Published

31-03-2020

How to Cite

1.
Shimouchi A, Tsuda Y, Komukai J, Matsumoto K, Yoshida H, Ohkado A. Characteristics of individuals with tuberculosis in an urban, poor population in Osaka City, Japan — a case-control study. Western Pac Surveill Response J [Internet]. 2020 Mar. 31 [cited 2026 Mar. 21];11(1). Available from: https://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/598

Issue

Vol. 11 No. 1 (2020): January – March

Section

Original Research

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