Systematic sequencing of imported cases leads to detection of SARS-CoV-2 B.1.1.529 (Omicron) variant in central Viet Nam

Systematic sequencing of SARS-CoV-2 in Viet Nam

Authors

  • Do Thai Hung Pasteur Institute in Nha Trang, Nha Trang, Viet Nam
  • Nguyen Bao Trieu Pasteur Institute in Nha Trang, Nha Trang, Viet Nam
  • Do Thi Thu Thuy U.S. Centers for Disease Control and Prevention, Hanoi, Viet Nam
  • Allison Olmsted U.S. Centers for Disease Control and Prevention, Hanoi, Viet Nam
  • Trinh Hoang Long Pasteur Institute in Nha Trang, Nha Trang, Viet Nam
  • Nguyen Duc Duy Pasteur Institute in Nha Trang, Nha Trang, Viet Nam
  • Huynh Kim Mai Pasteur Institute in Nha Trang, Nha Trang, Viet Nam
  • Bui Thi Thu Hien U.S. Centers for Disease Control and Prevention, Hanoi, Viet Nam
  • Nguyen Van Van Quang Nam Department of Health, Quang Nam, Viet Nam
  • Tran Van Kiem Quang Nam Center for Disease Control, Quang Nam, Viet Nam
  • Vo Thi Thuy Trang Quang Nam Center for Disease Control, Quang Nam, Viet Nam
  • Nguyen Truong Duy Quang Nam Center for Disease Control, Quang Nam, Viet Nam
  • Ton That Thanh Da Nang Center for Disease Control, Da Nang, Viet Nam
  • Huynh Van Dong Khanh Hoa Center for Disease Control, Khanh Hoa, Viet Nam
  • Philip L Gould U.S. Centers for Disease Control and Prevention, Hanoi, Viet Nam
  • Matthew R Moore U.S. Centers for Disease Control and Prevention, Hanoi, Viet Nam

DOI:

https://doi.org/10.5365/wpsar.2022.13.4.977

Keywords:

SARS-CoV-2, public health surveillance, whole genome sequencing, imported infectious diseases, Vietnam

Abstract

As authorities braced for the arrival of the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), infrastructure investments and government directives prompted action in central Viet Nam to establish capacity for genomic surveillance sequencing. From 17 November 2021 to 7 January 2022, the Pasteur Institute in Nha Trang sequenced 162 specimens from 98 150 confirmed SARS-CoV-2 cases in the region collected from 8 November to 31 December 2021. Of these, all 127 domestic cases were identified as the B.1.617.2 (Delta) variant, whereas 92% (32/35) of imported cases were identified as the B.1.1.529 (Omicron) variant, all among international flight passengers. Patients were successfully isolated, enabling health-care workers to prepare for additional cases. Most (78%) of the 32 Omicron cases were fully vaccinated, suggesting continued importance of public health and social measures to control the spread of new variants.

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Published

23-11-2022

How to Cite

Do, H., Nguyen, T., Do, T., Olmsted, A., Trinh, L., Nguyen, D., Huynh, M., Bui, H., Nguyen, V., Tran, K., Vo, T., Nguyen, D., Ton, T., Huynh, D., Gould, P. L., & Moore, M. R. (2022). Systematic sequencing of imported cases leads to detection of SARS-CoV-2 B.1.1.529 (Omicron) variant in central Viet Nam: Systematic sequencing of SARS-CoV-2 in Viet Nam. Western Pacific Surveillance and Response, 13(4), 4. https://doi.org/10.5365/wpsar.2022.13.4.977

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Section

COVID-19: Brief Report

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