National burden of influenza-associated hospitalizations in Cambodia, 2015 and 2016

Authors

  • Vanra Ieng World Health Organization, Country Office, Phnom Penh, Cambodia
  • M Ximena Tolosa National Centre for Epidemiology and Population Health, The Australian National University, Australia; WHO Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, Australia https://orcid.org/0000-0002-7775-0091
  • Bunchhoeng Tek Communicable Disease Control Department, Ministry of Health, Phnom Penh, Cambodia
  • Borann Sar Centers for Disease Control and Prevention, Country Office, Phnom Penh, Cambodia
  • Kheng Sim Communicable Disease Control Department, Ministry of Health, Phnom Penh, Cambodia
  • Heng Seng Communicable Disease Control Department, Ministry of Health, Phnom Penh, Cambodia
  • Miliya Thyl Angkor Hospital for Children, Siem Reap, Cambodia
  • Chan Dara Svay Rieng Provincial Hospital, Cambodia
  • Mey Moniborin Kampong Cham Provincial Hospital, Cambodia
  • Rebekah J. Stewart Centers for Disease Control and Prevention, Atlanta, GA, USA
  • Leila Bell Emerging Disease Surveillance and Response, World Health Organization Regional Office for the Western Pacific, Manila, Philippines
  • Georgios Theocharopoulos World Health Organization, Country Office, Phnom Penh, Cambodia
  • Savuth Chin National Public Health Laboratory, National Institute of Public Health, Phnom Penh, Cambodia
  • Darapheak Chau National Public Health Laboratory, National Institute of Public Health, Phnom Penh, Cambodia
  • A Danielle Iuliano Centers for Disease Control and Prevention, Atlanta, GA, USA
  • Ann Moen Centers for Disease Control and Prevention, Atlanta, GA, USA
  • Reiko Tsuyuoka World Health Organization, Country Office, Phnom Penh, Cambodia
  • Erica L Dueger Centers for Disease Control and Prevention, Atlanta, GA, USA; Emerging Disease Surveillance and Response, World Health Organization Regional Office for the Western Pacific, Manila, Philippines
  • Sheena G Sullivan WHO Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, Australia; Department of Epidemiology, University of California, Los Angeles, CA, USA; School of Population and Global Health, University of Melbourne, Melbourne, Australia
  • Sovann Ly Communicable Disease Control Department, Ministry of Health, Phnom Penh, Cambodia

DOI:

https://doi.org/10.5365/wpsar.2018.9.5.011

Abstract

Introduction: The burden of influenza in Cambodia is not well known, but it would be useful for understanding the impact of seasonal epidemics and pandemics and to design appropriate policies for influenza prevention and control. The severe acute respiratory infection (SARI) surveillance system in Cambodia was used to estimate the national burden of SARI hospitalizations in Cambodia.

Methods: We estimated age-specific influenza-associated SARI hospitalization rates in three sentinel sites in Svay Rieng, Siem Reap and Kampong Cham provinces. We used influenza-associated SARI surveillance data for one year to estimate the numerator and hospital admission surveys to estimate the population denominator for each site. A national influenza-associated SARI hospitalization rate was calculated using the pooled influenza-associated SARI hospitalizations for all sites as a numerator and the pooled catchment population of all sites as denominator. National influenza-associated SARI case counts were estimated by applying hospitalization rates to the national population.

Results: The national annual rates of influenza-associated hospitalizations per 100 000 population was highest for the two youngest age groups at 323 for < 1 year and 196 for 1–4 years. We estimated 7547 influenza-associated hospitalizations for Cambodia with almost half of these represented by children younger than 5 years.

Discussion: We present national estimates of influenza-associated SARI hospitalization rates for Cambodia based on sentinel surveillance data from three sites. The results of this study indicate that the highest burden of severe influenza infection is borne by the younger age groups. These findings can be used to guide future strategies to reduce influenza morbidity.

Author Biography

M Ximena Tolosa, National Centre for Epidemiology and Population Health, The Australian National University, Australia; WHO Collaborating Centre for Reference and Research on Influenza, The Peter Doherty Institute for Infection and Immunity, Australia

Dr Ximena Tolosa is an applied epidemiology trainee completing the Australian Field Epidemiology Training Program at the WHO Collaborating Centre for Reference and Research on Influenza in Melbourne. She holds postgraduate qualifications in international public health and microbiology.

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Published

23-10-2018

How to Cite

1.
Ieng V, Tolosa MX, Tek B, Sar B, Sim K, Seng H, Thyl M, Dara C, Moniborin M, Stewart RJ, Bell L, Theocharopoulos G, Chin S, Chau D, Iuliano AD, Moen A, Tsuyuoka R, Dueger EL, Sullivan SG, Ly S. National burden of influenza-associated hospitalizations in Cambodia, 2015 and 2016. Western Pac Surveill Response J [Internet]. 2018 Oct. 23 [cited 2024 Nov. 22];9(5). Available from: https://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/627

Issue

Vol. 9 No. 5 (2018): Suppl 1 Centennial Influenza Pandemic

Section

Original Research

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