A community-based sero-epidemiological study of hepatitis B infection in Lianyungang, China, 2010

Authors

  • Zhang Ting-lu Lianyungang Municipal Center for Disease Control and Prevention, Lianyungang, Jiangsu Province, China.
  • Xiao Zhi-ping
  • Ling Hong-yu
  • Ge Chang-hong
  • Ying Liang
  • Ding Qiang
  • Xu Kai-ling
  • Mao Yan-ming
  • Du Yue-he
  • Zhu Ling-yang

DOI:

https://doi.org/10.5365/wpsar.2011.2.1.008

Abstract

Introduction: The 2010 targets of the China Hepatitis B Prevention Programme were a prevalence of hepatitis B surface antigen (HBsAg) less than 1.0% for children less than five years old and less than 6.0% for the total population. This survey assessed the prevalence of Hepatitis B infection in Lianyungang, Jiangsu province, China in 2009–2010.

Methods: Multistage sampling was used with 2372 subjects among 17 selected villages. Blood specimen collection and testing by enzyme-linked immunosorbnet assay (ELISA) were completed using the following markers for hepatitis infection: HBsAg and antibody to HBsAg (anti-HBs); hepatitis B e antigen (HBeAg) and antibody to HBeAg (anti-HBe); and hepatitis B core antibody (total anti-HBc). The data were analyzed with Epi Info, version 3.3.2.

Results: The prevalence of HBsAg was 2.4% (95% Confidence Interval [CI]: 1.8–3.0; Adjusted Prevalence [AP] 2.9%); anti-HBs prevalence was 51.1% (95% CI: 49.1–53.1; AP 49.2%) and total anti-HBc prevalence was 41.7% (95% CI: 39.8–43.7; AP 45.5%). The prevalence of HBsAg and total anti-HBc positivity increased from young to older age groups, yet the prevalence of anti-HBs positivity decreased from young to older age groups (P < 0.001 for all). There was no difference in the prevalences of HBsAg and anti-HBs among females and males (P = 0.108 and 0.089), but females had a higher prevalence than males for total anti-HBc positivity (P < 0.001).

Discussion: This survey showed that in 2010 the prevalence of HBsAg among children aged less than five years was lower than the national target of 1.0% and that the prevalence of HBsAg for the total population was lower than the national target of 6.0%.

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How to Cite

1.
Ting-lu Z, Zhi-ping X, Hong-yu L, Chang-hong G, Liang Y, Qiang D, Kai-ling X, Yan-ming M, Yue-he D, Ling-yang Z. A community-based sero-epidemiological study of hepatitis B infection in Lianyungang, China, 2010. Western Pac Surveill Response J [Internet]. 2013 May 30 [cited 2026 Apr. 6];3(3). Available from: https://ojs.wpro.who.int/ojs/index.php/wpsar/article/view/162

Issue

Vol. 3 No. 3 (2012): July – September

Section

Other topic - Original Research

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